South Africa Launches Landmark Maternal Nutrition Trial

A major national clinical trial was launched on 29 July 2026 at the Wits RHI Shandukani Clinical Research Site in Johannesburg to test whether a Multiple Micronutrient Supplementation tablet improves pregnancy outcomes compared with the iron and folic acid tablets currently provided to all pregnant women in the public healthcare system.

Poor maternal nutrition continues to contribute to low birth weight, premature birth and avoidable pregnancy complications across South Africa. The new MMS tablet combines iron, folic acid and additional essential vitamins and minerals in a single daily dose. Researchers will compare how well women adhere to the supplement, and whether it leads to healthier birth weights and fewer complications.

Zandile Kubeka, Deputy Director for Dietetics, Child and Youth Health at the National Department of Health, confirmed the study's potential to shape national policy. "Improving nutrition during pregnancy is one of the most effective ways to support healthy pregnancies and ensure children have the best possible start in life," she said.

Who is affected

Every pregnant woman in South Africa could eventually be affected if the trial leads to a change in standard national policy.

What you need to know

• Currently all pregnant women receive iron and folic acid free at public clinics.
• The trial tests whether a broader mix of nutrients works better.
• Findings are expected to guide national antenatal nutrition policy.

What you can do

All pregnant women should continue attending antenatal care and taking supplements provided by their clinic. If you are pregnant and wish to enrol in the trial, ask your healthcare provider whether a site is operating near you.

Sources

Every claim on this page is traceable. These are the documents it rests on.

1. Inner City Gazette 2 August 2026